Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bilateral prophylactic mastectomy decision making: A vignette study.

M Stefanek1, C Enger, J Benkendorf

  • 1Behavioral Research Program, Division of Cancer Control and Population Services, National Cancer Institute, 6130 Executive Boulevard/EPN 211, Bethesda, Maryland, 20892, USA. ms496r@nih.gov

Preventive Medicine
|September 10, 1999
PubMed
Summary

About 25% of women chose bilateral prophylactic mastectomy (BPM) as a follow-up care option. Worry and perceived risk significantly predicted this choice, highlighting the need for psychosocial support.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can obligate apomixis and more stable reproductive assurance explain the distributional successes of asexual triploids in Hieracium alpinum (Asteraceae)?

Plant biology (Stuttgart, Germany)·2018
Same author

Assessment of off-label use of denosumab 60 mg injection during the early postmarketing period using health insurance claims data.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
Same author

Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence.

Molecular psychiatry·2013
Same author

Biomarkers for smoking cessation.

Clinical pharmacology and therapeutics·2013
Same author

APOE ɛ4, an Alzheimer's disease susceptibility allele, and smoking cessation.

The pharmacogenomics journal·2012
Same author

Association of BDNF and COMT genotypes with cognitive processing of anti-smoking PSAs.

Genes, brain, and behavior·2011

Area of Science:

  • Oncology
  • Surgical Oncology
  • Preventive Medicine

Background:

  • Perception of bilateral prophylactic mastectomy (BPM) and its influencing factors, particularly family history of breast cancer, remain understudied.
  • Identifying key factors in selecting BPM for follow-up care is crucial for informed decision-making.

Purpose of the Study:

  • To investigate women's perceptions of bilateral prophylactic mastectomy (BPM).
  • To determine if family history of breast cancer influences the selection of BPM.
  • To identify factors predicting the choice of BPM for follow-up care.

Main Methods:

  • A vignette-based study involving predominantly Caucasian, well-educated women with (n=129) and without (n=104) family histories of breast cancer.
  • Participants selected between standard screening (clinical breast exam, breast self-exam, mammography) and BPM.

Related Experiment Videos

Main Results:

  • No significant difference in BPM selection rates between women with and without family history (29.5% vs 22.1%).
  • Women with a family history reported higher levels of worry about breast cancer (34.4% vs 15.7%).
  • Multivariate analysis identified worry and estimated 10-year risk as significant predictors for choosing BPM.

Conclusions:

  • Approximately 25% of participants opted for BPM, with most supporting its discussion for high-risk women.
  • Worry and risk perception are key factors influencing BPM selection and can be addressed through psychosocial or educational interventions.
  • Pre-surgical decision-making necessitates assessment of patient's worry and risk perception.