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The Earth's bounty: assessing and accessing soil microbial diversity
M R Rondon1, R M Goodman, J Handelsman
1Department of Plant Pathology, University of Wisconsin-Madison, 1630 Linden Drive, Madison, WI 53706, USA. mrr@plantpath.wisc.edu
Trends in Biotechnology
|September 11, 1999
Summary
Exploring microbial diversity reveals vast, uncultured microorganisms. New methods unlock their genetic and chemical potential for biology and biotechnology advancements.
Area of Science:
- Microbial Ecology
- Biotechnology
- Molecular Biology
Background:
- The study of microbial diversity is crucial for biological and biotechnological progress.
- Recent molecular microbial ecology research indicates a significantly underestimated extent of microbial diversity in natural environments.
- Understanding this diversity offers substantial opportunities for scientific and technological innovation.
Purpose of the Study:
- To discuss methods for analyzing microorganisms from natural environments without relying on traditional culturing techniques.
- To explore novel approaches for accessing the genetic and chemical resources of uncultured microorganisms.
- To highlight the importance of microbial diversity in advancing biological sciences and biotechnology.
Main Methods:
- Non-culturing techniques for microbial analysis in natural settings.
- Molecular microbial ecology approaches.
- Strategies for accessing microbial genetic and chemical resources.
Main Results:
- Identification of a vast and previously unrecognized microbial diversity in nature.
- Development and discussion of advanced methods for studying uncultured microbes.
- Establishment of new pathways to explore the genetic and chemical potential of these microorganisms.
Conclusions:
- The field of microbial diversity offers significant opportunities for biological and biotechnological breakthroughs.
- Non-culturing methods are essential for fully characterizing microbial ecosystems.
- Unlocking the resources of uncultured microorganisms will drive future innovation in science and industry.