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Topless optic disk syndrome without maternal diabetes mellitus
M Hashimoto1, K Ohtsuka, T Nakagawa
1Department of Ophthalmology, Sapporo Medical University, School of Medicine, Hokkaido, Japan.
American Journal of Ophthalmology
|September 11, 1999
Summary
Topless optic disk syndrome, a rare condition, can occur without maternal diabetes mellitus. This finding challenges previous assumptions linking the syndrome to maternal diabetes.
Area of Science:
- Ophthalmology
- Optic Nerve Disorders
Background:
- Topless optic disk syndrome (superior segmental optic hypoplasia) is a rare congenital anomaly.
- Maternal diabetes mellitus has been considered a potential risk factor.
Observation:
- Four patients presented with incidentally discovered inferior visual field defects.
- Ophthalmoscopic examinations revealed superiorly displaced central retinal artery entrances and thinning of superior peripapillary nerve fiber layers.
Findings:
- Clinical findings were consistent with superior segmental optic hypoplasia (topless disk).
- Crucially, none of the patients had mothers with a history of diabetes mellitus.
Implications:
- This study demonstrates that topless optic disk syndrome can occur independently of maternal diabetes.
- It suggests that other etiological factors may be involved in the development of this condition.