[Virus reproduction in cell cultures synchronized by macromolecular platinum complexes]

A new method of application of platinum macromolecular complex poly{hexacis[chloroamine aquaplatinum (II)]}-mu-deoxyribonucleate (MCP) as a cell cycle synchronization inductor has been developed. The process of some RNA-genome viruses reproduction in cell cultures synchronized by MCP was studied. It was shown that the amount of virus protection in such cultures under special conditions can be increased 100-350 times without increasing the cell substrate amount. The obtained results may be used in biotechnology to increase production of virus antigens and vaccines.