Treatment of experimental burn wound sepsis by postburn immunization with polyvalent Pseudomonas antigen
Related Experiment Video
Updated: Oct 19, 2026
07:16
Swine Model of Biofilm Infection and Invisible Wounds
Published on: June 16, 2023
F C Nance1, J L Hines, R E Fulton
1Department of Surgery, Louisiana State University School of Medicine, New Orleans, USA.
Surgery
|July 1, 1970
Abstract:
1. Vaccination with a new heptavalent Pseudomonas aeruginosa antigen was found to reduce mortality rates from experimental pseudomonal burn wound sepsis. 2. Adjunctive use of the heptavalent vaccine improved survival of animals with pseudomonal sepsis which were treated with topical antibiotics. 3. Elevated antibody titers following vaccination could be correlated with survival in this model.
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01:22Burn Injuries
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
01:24Smallpox
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