Mathematical modeling in mRNA therapeutics: towards a pathway to individualized treatment protocols

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Predictive Immune Modeling of Solid Tumors
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Elio Campanile1,2, Elisa Pettinà2,3, Luca Marchetti2,3

  • 1Department of Mathematics, University of Trento, Trento, Italy.

Expert Review of Clinical Pharmacology
|November 2, 2026
PubMed
Abstract

Keywords:
Lipid nanoparticles (LNPs)mRNA therapeuticsmathematical modelingmultiscale modelingpharmacodynamics (pd)pharmacokinetics (pk)physiologically based pharmacokinetic (PBPK) modelingprecision medicinequantitative systems pharmacology (QSP)translational modeling

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