[The main clinico-neurological syndromes of prolonged hypokinesia]

Based on analysis of the nature and course of disorders in 81 volunteers as the sequel to strict horizontal (0 degree) or head-down (-4 degrees to -6 degrees) bed rest (hypokinesia) from seven days up to six months, neurological phenomenology of the following clinical syndromes was described: "acute" hemodynamics deviations, physical and thermal discomfort, astheno-neurotic developments, autonomous vascular dysfunction and trophic disturbances, neuromuscular disorders, statokinetic disorders, algesia, and degraded ability to do physical performance tests. Each of the above syndromes became perceptible at certain phases of bed rest, progressed as the time of hypokinesia grew and sharply aggravated early in the readaptation period on regaining the vertical posture and peaked during physical testing. Despite of the variety of physical exercises and supportive medicaments used during six months of bed rest, recovery of the health disorders took no less than two months of extensive therapeutic/rehabilitative treatment.