Related Experiment Video
Updated: Aug 8, 2026
Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
Published on: June 17, 2015
[Morphologic changes in the rat inferior olive after its neurotoxic destruction with different doses of
A B Melik-Musian1, E A Oganesian, V V Fanardzhian
1Laboratory of Central Nervous System Physiology, L.A. Orbeli Institute of Physiology, National Academy of Sciences of Armenia, Yerevan.
Abstract:
Neurotoxic effect of 3 acetylpyridine administered in different doses to adult outbred albino rats caused morphological changes in neurons of inferior olive: nucleus translocation towards cell body periphery with central chromatolysis, cytoplasm homogenisation complete dissolution of chromatophilic substance, disappearance of cell contours with glia preservation. The most severe lesion of the nervous tissue was observed in basal olive and dorsal accessory olive in all cases studied. Majority of neurons remained unchanged in medial accessory olive and its subdivisions.
More Related Videos
08:27Establishment of a Valuable Mimic of Alzheimer's Disease in Rat Animal Model by Intracerebroventricular Injection of Composited Amyloid Beta Protein
Published on: July 29, 2018
07:57An Alternative Approach to Study Primary Events in Neurodegeneration Using Ex Vivo Rat Brain Slices
Published on: April 11, 2018