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[Cerebral deep vein thrombosis: three cases].

C Di Roio1, C Jourdan, H Yilmaz

  • 1Département d'Anesthésie-Réanimation, Hôpital neurologique et neurochirurgical Pierre Wertheimer, Lyon.

Revue Neurologique
|September 16, 1999
PubMed
Summary

Cerebral venous sinus thrombosis is a rare condition in adult males, often presenting with severe neurological symptoms. Despite intensive care, all reported cases were fatal, highlighting diagnostic and therapeutic challenges.

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Area of Science:

  • Neurology
  • Vascular Medicine

Background:

  • Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke.
  • Diagnosis can be challenging, particularly in non-traditional presentations.

Observation:

  • Three adult male cases of cerebral internal venous thrombosis are presented.
  • Clinical manifestations included headaches, vomiting, dizziness, coma, intracranial hypertension, and cardiocirculatory arrest.
  • Diagnostic imaging (CT scan, cerebral angiography) confirmed thrombosis, revealing hemorrhagic/ischemic lesions, cerebral edema, and hydrocephalus.

Findings:

  • No patient survived despite comprehensive intensive care, including anticoagulation, CSF drainage, osmotherapy, and mechanical ventilation.
  • Pre-existing conditions like sickle cell disease, radiotherapy for pineal tumors, or suspected autoimmune disease were noted in two and three cases, respectively.

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  • The rarity and diagnostic difficulty of CVST are emphasized.

    • Implications:

    • This case series underscores the poor prognosis of cerebral internal venous thrombosis.
    • It highlights the need for increased awareness and timely diagnosis of CVST.
    • Further research into optimal treatment strategies for this rare condition is warranted.