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Related Experiment Videos

Electrogastrography in cyclic vomiting syndrome.

S K Chong1

  • 1Department of Pediatric Gastroenterology and Nutrition, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, USA.

Digestive Diseases and Sciences
|September 18, 1999
PubMed
Summary
This summary is machine-generated.

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Cyclic vomiting syndrome (CVS) in children is linked to abnormal gastric myoelectrical activity. Electrogastrography (EGG) revealed significant tachygastria in symptomatic children, correlating with delayed gastric emptying.

Area of Science:

  • Gastroenterology
  • Pediatrics
  • Physiology

Background:

  • Cyclic vomiting syndrome (CVS) in children presents with characteristic periodicity.
  • Abnormal gastric myoelectrical activity is a potential underlying cause.
  • Cutaneous electrogastrography (EGG) can detect gastric myoelectrical abnormalities.

Purpose of the Study:

  • To investigate the role of abnormal gastric myoelectrical activity in children with CVS.
  • To compare EGG findings and gastric emptying in symptomatic, asymptomatic, and control children.

Main Methods:

  • Electrogastrography (EGG) was performed on 15 children with CVS (8 symptomatic, 7 asymptomatic) and controls.
  • Relative tachygastria activity (RTA) or power ratio was calculated.
  • Gastric emptying was assessed using 99mTc scintiscans in 28 CVS children and 8 controls.

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Main Results:

  • Symptomatic CVS children showed significant tachygastria, especially postprandially, differing from asymptomatic and control groups.
  • Abnormal EGGs and higher RTA were associated with delayed gastric emptying in CVS children.
  • 75% of CVS children exhibited delayed gastric emptying, while 25% showed abnormal EGG with tachygastria.

Conclusions:

  • Abnormal gastric myoelectrical activity, particularly tachygastria, is prevalent in children with CVS.
  • These abnormalities correlate with delayed gastric emptying, suggesting a role in CVS pathogenesis.
  • EGG is a valuable tool for assessing gastric dysrhythmia in pediatric CVS.