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Updated: Aug 7, 2026

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures
Published on: November 2, 2015
[The adaptational intracellular mechanisms regulating energy homeostasis during intermittent normobaric hypoxia]
N P Lebkova1, A Ia Chizhov, Iu I Bobkov
1Russian Medical Academy of Postgraduation Education, Moscow, Russia.
Abstract:
Rats trained to intermittent normobaric hypoxia (INH) developed an increase of the glycogen contents in the heart and liver parenchymatous cells. Fatty acids seem to be the main source for synthesis of the intracellular glycogen. The intracellular transformation of the lipid energy substrate into the carbohydrates maintains the energy homeostasis in hepatocytes and cardiomyocytes during hypoxic intervals of the INH thus creating the necessary conditions. This kind of regulating the substance supply of the cell energy supports the organism stability under various effects.
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