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Colonic manifestations of multiple endocrine neoplasia type 2B: report of four cases
S R Grobmyer1, J G Guillem, D S O'Riordain
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Diseases of the Colon and Rectum
|September 25, 1999
Abstract:
Multiple endocrine neoplasia type 2B is best known for its endocrine manifestations and typical phenotype. The gastrointestinal manifestations, however, are also an important and commonly unrecognized component of the syndrome. We present four cases that demonstrate the varied presentation of patients with colonic manifestations of multiple endocrine neoplasia type 2B. We discuss the cause, diagnostic significance, and management of the colonic disease that is a component of multiple endocrine neoplasia type 2B.