Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A three-dimensional cerebrovascular flow phantom.

R Fahrig1, H Nikolov, A J Fox

  • 1Department of Medical Biophysics, University of Western Ontario, London Health Sciences Centre and The J. P. Robarts Research Institute, Canada.

Medical Physics
|September 29, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms.

AJNR. American journal of neuroradiology·2023
Same author

High tibial osteotomy to neutral alignment improves medial knee articular cartilage composition.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2021
Same author

The Magellanic Corona as the key to the formation of the Magellanic Stream.

Nature·2020
Same author

Extending the dynamic range of biomedical micro-computed tomography for application to geomaterials.

Journal of X-ray science and technology·2019
Same author

Investigation of combined kV/MV CBCT imaging with a high-DQE MV detector.

Medical physics·2018
Same author

Motion compensation for cone-beam CT using Fourier consistency conditions.

Physics in medicine and biology·2017
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Researchers created a life-sized 3D model of cerebral vasculature for studying blood flow. This accurate flow phantom mimics in vivo conditions, aiding research in neurovascular diseases and treatments.

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Fluid Dynamics

Background:

  • Cerebral vasculature modeling is crucial for understanding neurovascular diseases.
  • Accurate flow phantoms are needed to simulate in vivo conditions for research.

Purpose of the Study:

  • To construct a life-sized, three-dimensional (3D) rigid flow-through model of the cerebral vasculature.
  • To validate the geometric accuracy and flow dynamics of the fabricated model against published physiological data.

Main Methods:

  • Fabrication of a 3D cerebral vasculature phantom using numerically controlled machining based on published vessel dimensions.
  • Inflow via carotid and vertebral arteries; outflow via anterior, middle, and posterior cerebral arteries.
  • Geometric accuracy assessment using high-resolution MR and CT imaging; flow dynamics evaluation by comparing simulated and in vivo measurements.

Related Experiment Videos

Main Results:

  • The model's measured vessel diameters agreed with prescribed values to within 4%.
  • Flow dynamics, including waveform shape and flow division, closely mimicked in vivo conditions, with an average deviation of 16%.
  • 3D magnetic resonance angiography, digital subtraction angiography, and computed rotational angiography images were successfully acquired.

Conclusions:

  • A life-sized, geometrically accurate, and hemodynamically representative 3D flow phantom of the cerebral vasculature has been successfully constructed.
  • This validated phantom can be used to mimic physiological situations for advanced neurovascular research and imaging technique development.