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Calretinin-immunoreactive neurons in rostral migratory stream: neuronal differentiation
T Kato1, K Yokouchi, Z Li
1Department of Anatomy, Shinshu University School of Medicine, Matsumoto, Japan.
Abstract:
The purpose of the present study was to examine immunohistochemically the expression of nestin and polysialylated neural cell adhesion molecule in calretinin-immunoreactive neurons of the rostral migratory stream, the restricted pathway through which neuronal precursor cells migrate towards the olfactory bulb. Using mirror sectioning, calretinin-immunoreactive neurons of the rostral migratory stream were shown to co-express nestin (20.8%) and polysialylated neural cell adhesion molecule (61.8%). The results show that calretinin-immunoreactive neurons in the rostral migratory stream still express immature neural and neuronal phenotypes.