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Related Experiment Videos

Persistent cloaca in a cynomolgus monkey (Macaca fascicularis).

R W Lewis, M C Palazzo, J C Kim

    Journal of Medical Primatology
    |January 1, 1978
    PubMed
    Summary
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    A persistent cloaca, a rare congenital anomaly, was identified in a 15-year-old female cynomolgus monkey. This is the first documented case in nonhuman primates, offering insights into embryological defects.

    Area of Science:

    • Reproductive Biology
    • Developmental Biology
    • Primate Medicine

    Background:

    • Persistent cloaca is a rare congenital anomaly where the rectum, bladder, and vagina or uterus exist as a single common channel.
    • Congenital anomalies in nonhuman primates are crucial for understanding human development and disease.
    • Previous reports of cloacal anomalies have been limited to human neonates.

    Observation:

    • A 15-year-old female cynomolgus monkey presented with a persistent cloaca.
    • This represents the first reported instance of this anomaly in a nonhuman primate.
    • Detailed anatomical findings were documented, highlighting the embryologic defect.

    Findings:

    • The persistent cloaca in this cynomolgus monkey demonstrates a significant embryologic defect.

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  • Anatomical findings correlated with the known embryological basis of cloacal malformations.
  • This case provides a unique opportunity to study the developmental pathology of cloaca in a primate model.

    • Implications:

    • This finding expands the understanding of persistent cloaca beyond human medicine into nonhuman primate models.
    • The case offers valuable insights into the embryological origins and anatomical manifestations of cloacal anomalies.
    • Further research in nonhuman primates may elucidate genetic or environmental factors contributing to cloacal malformations.