[Mucosal morphology in the latent form of terminal ileitis in children based on biopsy data]
1Research Institute of Pediatric Gastroenterology, Nizhny Novgorod.
Abstract:
Morphological study of serial section biopsies from 22 children was made to develop new diagnostic criteria of a latent form of terminal ileitis. The following changes were observed: fibroblastic reaction around the lymphoid follicles, degenerative changes of enterocytes close to the lymphoid follicles; disruption of basal membrane over the lymphoid follicles; penetration of lymphoid cells into the intestinal lumen and their adhesion to the apical membrane of enterocytes; neuroma-like structures as an issue of productive vasculitis. The frequency of the symptoms above 62% does not depend on the sex, age and treatment method.
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