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Down's syndrome screening in the UK in 1998

N J Wald, W J Huttly, C F Hennessy

    Lancet (London, England)
    |October 16, 1999
    PubMed

    Insights

    Antenatal screening for Down's syndrome using serum or ultrasound markers has risen. A UK survey from 1998 shows increased screening compared to 1991 and 1994.

    Area of Science:

    • Medical screening
    • Prenatal diagnostics
    • Genetics

    Background:

    • Increased utilization of antenatal screening for Down's syndrome over the past decade.
    • Focus on serum and ultrasound markers for Down's syndrome detection.
    • Comparative analysis of UK screening practices in 1991, 1994, and 1998.

    Discussion:

    • Trends in Down's syndrome screening uptake.
    • Comparison of screening methodologies and their prevalence.
    • Evolution of antenatal screening policies and practices in the UK.

    Key Insights:

    • Significant rise in antenatal screening for Down's syndrome.
    • Data from 1998 survey indicates continued expansion of screening programs.
    • Comparative analysis highlights changes in screening prevalence over time.

    Outlook:

    • Potential for further advancements in Down's syndrome screening technologies.
    • Implications for genetic counseling and prenatal care.
    • Future trends in population-based screening programs.

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