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A direct method for the formation of peptide and carbohydrate dendrimers
J P Mitchell1, K D Roberts, J Langley
1School of Chemistry, The University of Melbourne, Parkville, Victoria, Australia.
Bioorganic & Medicinal Chemistry Letters
|October 16, 1999
Abstract:
Two new methods for the modification of PAMAM dendrimers have been developed which allow the covergent synthesis of either peptide or carbohydrate-bearing dendrimer molecules. Both methods involve condensation between hydroxylamino nucleophiles and appropriate carbonyl-bearing reaction partners.