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[Magnetic resonance angiography of the renal arteries]
Abstract:
Initially, the clinical use of magnetic resonance angiography (MRA) in the abdomen has been restricted because of motion and flow related artifacts. The advent of high performance gradient systems made possible the development of 3D gadolinium-enhanced MRA techniques and expanded the clinical applications of MRA into the abdominal area, particularly for the investigation of renal arteries. This technique is safe, because the administered contrast agent (gadolinium) is free of clinically detectable nephrotoxicity and has a low incidence of allergic reactions. Moreover, contrast MRA also eliminates the risks of ionizing radiation which allows repeating the examination without the accumulation of radiation exposure. The main disadvantages of the technique are its low availability and the fact that the use of contrast agents for this procedure is still not reimbursed by the social security. Many studies demonstrated that contrast MRA allows for the reliable assessment of renal artery morphology and pathologic states. Furthermore, within a single MR examination a comprehensive approach including renal artery morphology, hemodynamic significance of any stenosis and kidney perfusion is available. In this paper, we provide a review of the literature concerning the clinical performance of contrast MRA for the renal arteries and suggest its rationale for the investigation of patients suspected of renovascular disease in our specific environment.
Insights
Gadolinium-enhanced magnetic resonance angiography (MRA) is a safe and effective tool for evaluating renal arteries, offering comprehensive assessment of renovascular disease without radiation exposure.
Area of Science:
- Medical Imaging
- Radiology
- Cardiovascular Imaging
Context:
- Abdominal magnetic resonance angiography (MRA) was initially limited by motion and flow artifacts.
- Advancements in gradient systems enabled 3D gadolinium-enhanced MRA for abdominal applications, especially renal arteries.
Purpose:
- To review the clinical performance of contrast-enhanced MRA for renal arteries.
- To suggest the rationale for using contrast MRA in patients with suspected renovascular disease.
Summary:
- 3D gadolinium-enhanced MRA is a safe technique with no clinically detected nephrotoxicity or significant allergic reactions.
- It avoids ionizing radiation, allowing for repeat examinations without cumulative exposure.
- Key limitations include limited availability and lack of social security reimbursement for contrast agents.
Impact:
- Contrast MRA reliably assesses renal artery morphology and pathology.
- It provides a comprehensive evaluation including hemodynamics and kidney perfusion in a single examination.
- This review supports the use of contrast MRA for diagnosing renovascular disease.