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Updated: Aug 11, 2026

Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes
Published on: July 28, 2017
Expression of the highly conserved RNA binding protein KOC in embryogenesis
F Mueller-Pillasch1, B Pohl, M Wilda
1Department of Internal Medicine I, University of Ulm, Germany. frederike.mueller-pillasch@medizin.uni-ulm.de
Abstract:
The human KOC gene which is highly expressed in cancer shows typical structural features of an RNA binding protein. We analyzed the temporal and spatial expression pattern of KOC in mouse embryos at different gestational ages. The expression of KOC seems to be ubiquitous at early stages. During advanced gestation highest KOC expression occurs in the gut, pancreas, kidney, and in the developing brain. The expression pattern of KOC was compared to its Xenopus homologue Vg1-RBP during frog development. Similar expression was found in these organs suggesting an important functional role of the homologous proteins in embryonic development.
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