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Updated: Oct 18, 2026

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
Published on: August 9, 2024
Evolution of pulmonary perfusion defects demonstrated with contrast-enhanced dynamic MR perfusion imaging
N R Howarth1, C Beziat, Y Berthezène
1Department of Radiology, Hôpital Cardiovasculaire et Pneumologique Louis Pradel, 59 boulevard Pinel, BP Lyon-Montchat, F-69394 Lyon 03, France.
Abstract:
Pulmonary perfusion defects can be demonstrated with contrast-enhanced dynamic MR perfusion imaging. We present the case of a patient with a pulmonary artery sarcoma who presented with a post-operative pulmonary embolus and was followed in the post-operative period with dynamic contrast-enhanced MR perfusion imaging. This technique allows rapid imaging of the first passage of contrast material through the lung after bolus injection in a peripheral vein. To our knowledge, this case report is the first to describe the use of this MR technique in showing the evolution of peripheral pulmonary perfusion defects associated with pulmonary emboli.
Insights
Dynamic contrast-enhanced MR perfusion imaging effectively visualizes pulmonary perfusion defects. This case report highlights its use in tracking post-operative pulmonary emboli in a patient with pulmonary artery sarcoma.
Area of Science:
- Radiology
- Cardiovascular Imaging
- Oncology
Background:
- Pulmonary artery sarcoma is a rare malignancy.
- Pulmonary emboli can occur post-operatively, complicating patient management.
- Dynamic contrast-enhanced MR perfusion imaging offers a method to assess lung perfusion.
Observation:
- A patient with pulmonary artery sarcoma developed a post-operative pulmonary embolus.
- Dynamic contrast-enhanced MR perfusion imaging was utilized for follow-up.
- The technique captured the evolution of peripheral pulmonary perfusion defects.
Findings:
- Contrast-enhanced dynamic MR perfusion imaging successfully demonstrated pulmonary perfusion defects.
- The study illustrates the utility of this MR technique in a specific clinical scenario.
- Serial imaging showed changes in perfusion related to pulmonary emboli.
Implications:
- This case suggests dynamic contrast-enhanced MR perfusion imaging is valuable for monitoring pulmonary emboli.
- The findings may enhance the understanding of perfusion dynamics in complex oncological cases.
- This technique could be a useful tool in managing patients with pulmonary artery sarcoma and thromboembolic complications.
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