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Recording the evoked canine detrusor electromyogram
J R Scheepe1, S Bross, S Schumacher
1Department of Urology, Universitätsklinikum Mannheim gGmbH, Mannheim, Germany.
Neurourology and Urodynamics
|October 26, 1999
Summary
Researchers developed a method to record detrusor electromyograms (detrusor-EMG) in dogs, correlating EMG signals with bladder contractions. This technique shows promise for diagnosing bladder dysfunctions and detrusor myopathies.
Area of Science:
- Urology
- Neuroscience
- Physiology
Background:
- Increasing interest in detrusor disorders and myopathies necessitates improved diagnostic tools.
- Current diagnostic methods for bladder dysfunction may benefit from electrophysiological assessment.
Purpose of the Study:
- To investigate the feasibility of recording detrusor electromyogram (detrusor-EMG) in an animal model.
- To correlate detrusor-EMG activity with bladder contractions and pressure changes.
Main Methods:
- Electromyographic activity of the detrusor smooth muscle was recorded in six anesthetized dogs.
- Recordings were taken during sacral root stimulation and spontaneous bladder contractions.
- Time domain and power spectrum analysis were employed to analyze the detrusor-EMG signals.
Main Results:
- A high correlation was observed between detrusor-EMG recordings and bladder contractions.
- The clearest correlation with intravesical pressure rise occurred in the frequency band above 3 Hz.
- Spike duration ranged from 100-250 ms with amplitudes of 100-500 microV; low-frequency activity (<1 Hz) was likely artifactual.
Conclusions:
- Smooth muscle electromyogram recordings from the detrusor are feasible.
- The established animal model can be used for pathophysiological investigations of bladder dysfunction and detrusor myopathies.
- The physiological relevance of sub-Hertz detrusor-EMG signals requires further investigation.
