A protocol system for testing biohazardous materials in an impact biomechanics research facility

Area of Science:

• Biomechanics
• Occupational Safety
• Infectious Disease Control

Background:

• Cadaveric tissue use in research poses risks of bloodborne pathogen exposure (e.g., HIV, hepatitis B).
• Pathogens can remain viable in cadavers for extended periods post-mortem.
• Impact biomechanics research facilities require stringent safety measures for handling biological materials.

Purpose of the Study:

• To present a comprehensive protocol system for the safe handling of cadaveric tissue in an impact biomechanics research setting.
• To detail methods for minimizing occupational exposure to bloodborne pathogens.
• To ensure compliance and proficiency in safety procedures for all laboratory personnel.

Main Methods:

• Development of a protocol system including a review process and checklists.
• Implementation of initial blood screening for incoming cadaveric tissue.
• Adoption of universal precautions, treating all tissue as potentially infectious.
• Mandatory training, signing, and proficiency demonstration for all lab employees.
• Annual individual protocol reviews.

Main Results:

• The protocol system has been effective in minimizing exposure risks over a 6-year period.
• Initial blood screening successfully prevents infectious tissue entry.
• Universal precautions mitigate exposure risks during tissue handling.
• Mandatory training ensures personnel are equipped to follow safety procedures.

Conclusions:

• The presented protocol system is effective in managing risks associated with cadaveric tissue in biomechanics research.
• A combination of screening, universal precautions, and rigorous training ensures a safe laboratory environment.
• The protocol provides a robust framework for handling biohazardous materials in research settings.