[Complex formation of di-oligodeoxyadenylyl-5',5'-pyrophosphatess with polyuridylic acid]

The complex formation of P1,P2-bis-trideoxyadenylyl-, P1-trideoxyadenylyl, P2-hexadeoxyadenylyl and P1,P2-bis-deoxyadenylyl-5',5-pyrophosphates with polyuridylic acid has been studied. It is shown that these compounds form triple-stranded complexes with poly-U, which have much the same absorption and circular dichroism spectra as those of (oligo-dA).2(poly-U). These results are considered as a support of an earlier suggestion about the irregular relative orientations of the oligodeoxyadenylates in the triple-stranded complexes with poly-U.