Introduction: molecular diagnostics in hematology

Advances in molecular biology of the last 30 tears have transformed the field of hematology. Molecular analysis has clarified the pathogenesis of a host of hematologic disorders, including hemoglobinopathies, coagulation disorders, hypercoaguable states, and hematologic malignancies. This volume is aimed at bringing these compelling advances in molecular biology research to the bedside. Through progress in the molecular understanding of hematology, great strides have been made in our ability to diagnose and treat patients with hematologic disease. These advances in turn have given rise to more questions that will guide future studies of the biology of hematopoietic abnormalities and continue the exciting interaction of basic science and clinical medicine.