Anti-AIDS agents. Part 36: 17-carboxylated steroids as potential anti-HIV agents

The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies.

The New England journal of medicine·1996

Interaction between human tRNA synthetases involves repeated sequence elements.

Proceedings of the National Academy of Sciences of the United States of America·1996

Unusually stable helical kink in the antimicrobial peptide--a derivative of gaegurin.

FEBS letters·1996

Decreased expression of phospholipase C-beta 2 isozyme in human platelets with impaired function.

Blood·1996

Abolition of spindle oscillations by serotonin and norepinephrine in the ferret lateral geniculate and perigeniculate nuclei in vitro.

Neuron·1996

Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.

Journal of natural products·1996

Design, synthesis, and biological evaluation of novel dihydropyrimidinone imines as potent anticancer agents targeting AKT to induce cell cycle arrest and apoptosis in breast Cancer cells.

Bioorganic & medicinal chemistry·2026

Design, synthesis, biological and computational evaluation of Thieno[3,2-d]pyrimidine-based inhibitors of JAK3 kinase.

Bioorganic & medicinal chemistry·2026

Design, synthesis and biological evaluation of a series of new, potent FLT3 PROTAC degraders with rigid linkers.

Bioorganic & medicinal chemistry·2026

An in vitro comparative study of cefiderocol, siderophore-aztreonam and siderophore-daptomycin conjugates against select gram-negative bacteria.

Bioorganic & medicinal chemistry·2026

Redirecting MurD inhibitor preference toward MurD2 through glutamate stereochemical inversion.

Bioorganic & medicinal chemistry·2026

Structural optimization of 2-(2-aminopyridin-4-yl)-N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as potent interleukin-1 receptor-associated kinase 4 inhibitors.

Bioorganic & medicinal chemistry·2026

Pharmacovigilance in the treatment of cutaneous leishmaniasis: adverse event profile at a reference center.

Revista da Sociedade Brasileira de Medicina Tropical·2026

Total synthesis as a critical tool for structural revision of natural products.

Chemical communications (Cambridge, England)·2026

Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review).

Molecular medicine reports·2026

Disproportionate reporting of seizures with histamine H1 receptor antagonists: The role of drug generation and brain H1 receptor occupancy assessed using the Japanese Adverse Drug Event Report database.

International journal of clinical pharmacology and therapeutics·2026

Discovery of tricyclic benzo[4,5]imidazo[2,1-b]thiazole-3-hydroxyindolin-2-one hybrids as selective MAO-B and cholinesterase inhibitors.

RSC advances·2026

Simultaneous exploitation of phaeanthine - a bisbenzylisoquinoline alkaloid for dual anti-metastatic and anti-angiogenic potential by disruption of Akt/NF-κB/MMP regulatory pathways.

RSC medicinal chemistry·2026

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Anti-AIDS agents. Part 36: 17-carboxylated steroids as potential anti-HIV agents

Related Concept Videos

The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies.

Interaction between human tRNA synthetases involves repeated sequence elements.

Unusually stable helical kink in the antimicrobial peptide--a derivative of gaegurin.

Decreased expression of phospholipase C-beta 2 isozyme in human platelets with impaired function.

Abolition of spindle oscillations by serotonin and norepinephrine in the ferret lateral geniculate and perigeniculate nuclei in vitro.

Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.

Design, synthesis, and biological evaluation of novel dihydropyrimidinone imines as potent anticancer agents targeting AKT to induce cell cycle arrest and apoptosis in breast Cancer cells.

Design, synthesis, biological and computational evaluation of Thieno[3,2-d]pyrimidine-based inhibitors of JAK3 kinase.

Design, synthesis and biological evaluation of a series of new, potent FLT3 PROTAC degraders with rigid linkers.

An in vitro comparative study of cefiderocol, siderophore-aztreonam and siderophore-daptomycin conjugates against select gram-negative bacteria.

Redirecting MurD inhibitor preference toward MurD2 through glutamate stereochemical inversion.

Structural optimization of 2-(2-aminopyridin-4-yl)-N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as potent interleukin-1 receptor-associated kinase 4 inhibitors.

Pharmacovigilance in the treatment of cutaneous leishmaniasis: adverse event profile at a reference center.

Total synthesis as a critical tool for structural revision of natural products.

Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review).

Disproportionate reporting of seizures with histamine H1 receptor antagonists: The role of drug generation and brain H1 receptor occupancy assessed using the Japanese Adverse Drug Event Report database.

Discovery of tricyclic benzo[4,5]imidazo[2,1-b]thiazole-3-hydroxyindolin-2-one hybrids as selective MAO-B and cholinesterase inhibitors.

Simultaneous exploitation of phaeanthine - a bisbenzylisoquinoline alkaloid for dual anti-metastatic and anti-angiogenic potential by disruption of Akt/NF-κB/MMP regulatory pathways.

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Anti-AIDS agents. Part 36: 17-carboxylated steroids as potential anti-HIV agents

Abstract:

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