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Published on: September 18, 2014
Suppressive mechanism of gastric motility by whole-body vibration
T Ishitake1, Y Miyazaki, H Ando
1Department of Environmental Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan. tishitak@med.kurume-u.ac.jp
Objective:
To investigate the mechanism of gastric motility suppression by exposure to whole-body vibration (WBV).
Methods:
The gastric motility was evaluated by electrogastrography (EGG) under food intake and autonomic nerve blocking agents in ten healthy volunteers. Sinusoidal vertical vibration with a frequency of 4 Hz (1.0 ms(-2) rms) was given to the subject for 10 min.
Results:
The amplitude of EGG wave and the power spectrum corresponding to the slow wave component was remarkably decreased by vibration exposure. Food intake enhanced the gastric motility about 2.5-fold in the power spectral density. During and after vibration exposure, the response mode was similar to those at fasting states. Under the influence of anticholinergic (scopolamine) and alpha-adrenergic blocking agents (prazosin), the power spectra were decreased. A further decrease was observed during vibration exposure. A beta-adrenergic blocking agent (propranolol) led to a marked increase in the amplitude of EGG and its power spectrum. With pretreatment by a beta-adrenergic blocking agent, however, vibration exposure reduced both of them.
Conclusions:
These results suggest that short-term exposure to WBV can suppress the gastric myoelectric activity, the responses on which may be mediating by neurohumoral effects as well as the mechanical effect of WBV.
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