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[Viruses as complicating factors during immune reactions]
1Laboratorium Wirusologii, Instytutu Immunologii i Terapii Doświadczalnej PAN, Wrocławiu.
Postepy Higieny I Medycyny Doswiadczalnej
|November 2, 1999
Abstract:
Different mechanisms engaged in modification of immune reactions by viruses are discussed in the review. The modifications cause the defence system ineffective in patogen elimination. The disturbing concerns antiviral activity of cytokines (i.e. IFNs, TNF alpha, IL-12), specific cytotoxicity of T lymphocytes and complement system. Proteins encoded by viruses (i.e. viral cytokines and receptors) and RNA molecules may be responsible for the effects.