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[Whooping cough today].

E Grimprel1

  • 1Hôpital Armand-Trousseau, Paris.

Presse Medicale (Paris, France : 1983)
|November 2, 1999
PubMed
Summary

Pertussis (whooping cough) epidemiology has shifted, with more infant cases and adult misdiagnosis. Early vaccination and boosters are crucial for controlling pertussis transmission in all age groups.

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Area of Science:

  • * Epidemiology of infectious diseases, specifically pertussis (whooping cough).
  • * Public health strategies for infectious disease control through vaccination programs.

Context:

  • * Pertussis epidemiology in France has significantly changed due to vaccination, with a shift from childhood to infant, adolescent, and adult cases.
  • * Adult pertussis often presents atypically, leading to misdiagnosis and continued transmission.
  • * Current guidelines recommend early vaccination and a booster at 11-13 years.

Purpose:

  • * To highlight the changing epidemiology of pertussis and its implications for diagnosis and control.
  • * To emphasize the importance of considering pertussis in adults with persistent cough.
  • * To advocate for early vaccination and timely boosters.

Summary:

  • * Bacterial isolates and PCR are key for early pertussis diagnosis in patients and contacts; PCR is covered by French health insurance.
  • * Serology aids retrospective diagnosis in vaccinated individuals, including children, adults, and infants' mothers via prepartum serum.
  • * Whole-cell pertussis vaccines are effective for infants, while acellular vaccines are suitable for boosters.

Impact:

  • * Improved diagnostic approaches and timely treatment can reduce pertussis transmission.
  • * Adherence to vaccination schedules, including boosters, is essential for maintaining herd immunity and protecting vulnerable populations.
  • * Public health awareness regarding adult pertussis symptoms can prevent misdiagnosis and facilitate earlier intervention.

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