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Related Experiment Videos

Finger pad tophi.

K F Chopra1, P Schneiderman, M E Grossman

  • 1Department of Dermatology, New York-Presbyterian Hospital, Columbia Presbyterian Center, New York, USA.

Cutis
|November 2, 1999
PubMed
Summary
This summary is machine-generated.

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Cyclosporine, an immunosuppressant, can cause tophaceous gout, a form of gout characterized by tophi deposits. This case highlights the risk of developing tophi on finger pads in patients treated with cyclosporine.

Area of Science:

  • Nephrology
  • Rheumatology
  • Immunology

Background:

  • Diuretic therapy is a known cause of hyperuricemia and gout.
  • Cyclosporine, an immunosuppressant medication, has been increasingly recognized as a potential cause of tophaceous gout.

Observation:

  • A 57-year-old male lung transplant recipient developed progressive renal insufficiency and hypertension six months after starting cyclosporine.
  • Ten months post-transplant, the patient presented with symmetrical tophi on his finger pads.

Findings:

  • This case adds to the literature on cyclosporine-induced tophaceous gout.
  • The patient's presentation of finger pad tophi is a rare manifestation.

Implications:

  • Clinicians should be vigilant for tophaceous gout in patients on cyclosporine, particularly those with renal impairment.

Related Experiment Videos

  • Early recognition and management of cyclosporine-associated hyperuricemia and gout are crucial to prevent complications.