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Axial length in patients with diabetes
L Pierro1, R Brancato, X Robino
1Department of Ophthalmology and Visual Sciences, Scientific Institute, San Raffaele Hospital, University of Milan, Italy.
Retina (Philadelphia, Pa.)
|November 5, 1999
Summary
Diabetic patients have shorter axial lengths than healthy individuals. Retinopathy in diabetes is linked to even shorter axial lengths, indicating retinal involvement.
Area of Science:
- Ophthalmology
- Diabetology
- Biometry
Background:
- Diabetes mellitus is a systemic disease with significant ocular complications.
- Retinopathy is a common microvascular complication of diabetes affecting the retina.
Purpose of the Study:
- To investigate the relationship between axial length and the presence and severity of diabetic retinopathy.
- To compare axial length in diabetic patients with and without retinopathy to healthy controls.
Main Methods:
- Biometry was performed on 157 diabetic patients and 157 healthy controls.
- Diabetic patients were categorized based on the presence and type of retinopathy (none, background, proliferative).
- Axial length was analyzed in relation to diabetes type, duration, retinopathy, and laser treatment, excluding myopia >24mm.
Main Results:
- Diabetic patients exhibited significantly shorter axial lengths (22.4±1.3 mm) compared to controls (23.4±1.3 mm).
- Shorter axial lengths were observed in diabetic patients with background (22.0±1.2 mm) and proliferative retinopathy (22.1±1.1 mm) versus those without retinopathy (23.2±1.4 mm).
- Retinopathy showed a negative correlation with axial length in multivariate analyses.
Conclusions:
- Diabetic patients, on average, have shorter axial lengths than non-diabetic individuals.
- The presence and severity of diabetic retinopathy are associated with reduced axial length within the diabetic population.