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Related Experiment Videos

Contrast-enhanced coronary MRA.

C H Lorenz1, L O Johansson

  • 1Center for Cardiovascular MR, Cardiovascular Division, Barnes-Jewish Hospital at Washington University Medical Center, St. Louis, MO 63110, USA. chl@ccmr.wustl.edu

Journal of Magnetic Resonance Imaging : JMRI
|November 5, 1999
PubMed
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Magnetic resonance imaging (MRI) aims to diagnose coronary artery disease. Challenges like motion and signal quality persist, requiring advancements in MRI techniques and contrast agents for reliable coronary imaging.

Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging

Background:

  • Coronary angiography using magnetic resonance imaging (MRI) is a long-standing goal for clinical diagnosis of coronary artery disease.
  • Key challenges in cardiac MRI include respiratory and cardiac motion, and suboptimal signal-to-noise (SNR) and contrast-to-noise ratios (CNR).

Purpose of the Study:

  • To discuss fundamental problems in MR coronary imaging strategies.
  • To review methods for improving SNR and CNR in MR coronary angiography.
  • To highlight the role of T1-shortening contrast agents in enhancing coronary imaging.

Main Methods:

  • Discussion of fundamental problems in MR coronary imaging.
  • Presentation of various methods to improve SNR and CNR.
  • Emphasis on T1-shortening contrast agents (extracellular and intravascular).

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Main Results:

  • Significant progress has been made in MR coronary imaging techniques.
  • Clinical success for widespread diagnosis of coronary artery disease remains unproven.

Conclusions:

  • Reliable MR coronary imaging requires synergistic advancements in acquisition techniques, respiratory compensation, post-processing, and contrast agents.
  • Future success depends on developing a robust solution applicable to diverse patient populations.