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Lack of association between schizophrenia and a pancreatic phospholipase A-2 gene (PLA2G1B) polymorphism
J Strauss1, X R Zhang, Y Barron
1Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA.
Psychiatric Genetics
|November 7, 1999
Abstract:
Patients with schizophrenia (DSM IV, n = 149) and controls (n = 180) participated in a case-control association study in which a trinucleotide repeat polymorphism of pancreatic phospholipase A2 group 1B (PLA2G1B) was examined. Both African-American and Caucasian populations were included in this USA sample. There were no significant case-control differences, therefore his study does not support an association between schizophrenia and a PLA2G1B polymorphism on chromosome 12.