What's new in pediatric organ transplantation

Current progress in organ transplantation is offering new hope for children who have end-stage heart, lung, liver, intestinal, and renal failure. Immunosuppressive regimens have been improved, and newer immunomodulatory strategies are evolving. New areas of investigation, such as genetic modification of xenograft tissues and organs, and strategies to induce tolerance of organs will be key areas of discovery in the next years, leading to increasing involvement of the generalist in the care of children requiring or recovering from transplantation.