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Related Experiment Videos

Recovery of bladder function after spinal cord transection.

U Jonas, L W Jones, E A Tanagho

    The Journal of Urology
    |May 1, 1975
    PubMed
    Summary

    Following spinal cord transection, dogs experienced spinal shock with urinary retention due to an unresponsive detrusor. This condition resolved as reflex activity returned, indicating the detrusor

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    Area of Science:

    • Veterinary Neurology
    • Urology
    • Neuroscience

    Background:

    • Spinal cord transection in dogs leads to a temporary loss of bladder function.
    • Understanding the mechanisms of urinary retention post-injury is crucial for treatment.

    Purpose of the Study:

    • To investigate the physiological basis of urinary retention during spinal shock in dogs.
    • To determine the duration and recovery patterns of detrusor areflexia after spinal cord injury.

    Main Methods:

    • Spinal cord transection was performed on canine subjects.
    • Postoperative monitoring included urinary retention assessment and detrusor pressure studies.
    • Bladder function was evaluated over several weeks.

    Main Results:

    • All dogs exhibited a spinal shock phase characterized by complete urinary retention and an areflexic detrusor, lasting 2-6 weeks.
    • Pressure studies confirmed detrusor unresponsiveness as the cause of retention.
    • Sphincteric dysfunction was considered a potential contributing factor.

    Conclusions:

    • Urinary retention in the acute phase post-spinal cord transection is primarily due to detrusor areflexia.
    • The detrusor eventually regains reflex activity, suggesting a potential for recovery of bladder function.
    • Further research into the role of the sphincteric mechanism is warranted.

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