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Current knowledge in the management of children and adolescents with sickle cell disease: Part 1, Physiological

K Simon1, M L Lobo, S Jackson

  • 1College of Nursing, University of South Carolina, Charleston 29425, USA.

Journal of Pediatric Nursing
|November 11, 1999
PubMed

Insights

This review covers managing sickle cell disease (SCD) in young people, detailing clinical issues and treatments. It offers recommendations for nursing care and future research to improve health outcomes.

Area of Science:

  • Pediatric Hematology
  • Clinical Nursing
  • Public Health

Background:

  • Sickle cell disease (SCD) is a genetic blood disorder significantly impacting children and adolescents.
  • Effective management requires understanding its complex physiological issues and clinical manifestations.
  • Current treatment strategies are evolving, necessitating updated knowledge for healthcare providers.

Purpose of the Study:

  • To provide a comprehensive review of the current knowledge on SCD management in pediatric and adolescent populations.
  • To discuss the physiological aspects, clinical presentations, and therapeutic interventions for SCD.
  • To outline prevention strategies (primary, secondary, tertiary) and offer recommendations for nursing practice and research.

Main Methods:

  • Literature review of existing research and clinical guidelines on SCD management.
  • Synthesis of information regarding the pathophysiology and clinical course of SCD in young individuals.
  • Analysis of current treatment modalities and preventive care approaches.

Main Results:

  • The review consolidates current understanding of SCD's clinical manifestations and physiological challenges.
  • It details various treatment options available for managing SCD in children and adolescents.
  • Prevention strategies across different levels are discussed, alongside identified gaps in nursing practice and research.

Conclusions:

  • Comprehensive management of pediatric SCD requires a multi-faceted approach addressing physiological, clinical, and psychosocial aspects.
  • Evidence-based nursing interventions and targeted research are crucial for improving the quality of life for young patients with SCD.
  • Continuous updates in management protocols and nursing education are essential for optimal patient outcomes.

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