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Related Experiment Video

Updated: Nov 26, 2025

Author Spotlight: Advancing Protein Structure Analysis for Drug Development

Author Spotlight: Advancing Protein Structure Analysis for Drug Development

Published on: March 8, 2024

Virus crystallography.

E E Fry¹, J Grimes, D I Stuart

¹Wellcome Trust Centre For Human Genetics, Oxford, UK.

Molecular Biotechnology

|November 11, 1999

Summary

This summary is machine-generated.

Virus crystallography reveals detailed structures of virus particles. This technique was applied to the complex bluetongue virus core, providing new insights into its atomic resolution structure.

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$Microcrystallography of Protein Crystals and In Cellulo Diffraction$

Microcrystallography of Protein Crystals and In Cellulo Diffraction

Published on: July 21, 2017

Area of Science:

Structural biology
Virology
Biophysics

Background:

Virus crystallography is a powerful technique for determining the three-dimensional structure of viruses at atomic resolution.
Understanding virus structure is crucial for developing antiviral therapies and vaccines.

Purpose of the Study:

To illustrate the application of virus crystallography methodology.
To determine the atomic resolution structure of a complex virus component.

Main Methods:

Virus crystallography was employed to analyze virus particles and their components.
The methodology was applied to the core of the bluetongue virus.

Main Results:

The study successfully determined the atomic resolution structure of the bluetongue virus core (700 Å).
The findings demonstrate the capability of virus crystallography for complex viral structures.

Conclusions:

Virus crystallography is effective for elucidating the structures of intact isometric viruses and their components.
The bluetongue virus core structure provides a detailed model for further research.