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[Acne and its treatment possibilities]
1Dermatologische Klinik, Universitätsspital Zürich. rboeni@derm.unizh.ch
Summary
Acne treatment faces challenges due to increasing antibiotic resistance in Propionibacterium acnes. New therapeutic strategies, including isotretinoin and antiandrogens, are needed to effectively manage this common skin condition and prevent scarring.
Area of Science:
- Dermatology
- Microbiology
Context:
- Acne vulgaris is a common, multifactorial skin disease impacting pilosebaceous units.
- Therapeutic goals include mitigating social distress and preventing acne scarring.
- Propionibacterium acnes plays a significant role in acne pathogenesis.
Purpose:
- To address the rising challenge of antibiotic resistance in Propionibacterium acnes.
- To present an updated treatment guide for acne management.
- To discuss the side effects associated with various acne treatment regimens.
Summary:
- A growing resistance of Propionibacterium acnes to antibiotics necessitates alternative therapeutic approaches.
- The study reviews current treatment options, including antibiotics, isotretinoin, and antiandrogens.
- Management strategies aim to reduce social isolation and minimize scarring.
Impact:
- Highlights the need for judicious antibiotic use in acne treatment.
- Provides guidance on alternative therapies like isotretinoin and antiandrogens.
- Informs clinicians on managing acne in the context of evolving bacterial resistance patterns.