Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comparing three preprocessing strategies for longitudinal data. An example in functional outcomes research.

P R Yarnold1, J Feinglass, W J McCarthy

  • 1Division of General Internal Medicine, Northwestern University Medical School, Chicago, IL 60611, USA.

Evaluation & the Health Professions
|November 11, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The association of state percent uninsured and the likelihood of low birth weight: evidence from the 2016-2019 Pregnancy Risk Assessment Monitoring System.

Public health·2023
Same author

Care home residents admitted to hospital through the emergency pathway: characteristics and associations with inpatient mortality.

The journal of the Royal College of Physicians of Edinburgh·2018
Same author

Androgyny and Sex-Typing as Continuous Independent Factors, and a Glimpse of the Future.

Multivariate behavioral research·2016
Same author

Prognostic significance of ST-segment depression on continuous electrocardiography in patients with acute ischemic neurologic events.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

Reporting of serious adverse events during cancer clinical trials to the institutional review board: an evaluation by the research on adverse drug events and reports (RADAR) project.

Journal of clinical pharmacology·2013
Same author

Consistency of NMR and mass spectrometry determinations of natural-abundance site-specific carbon isotope ratios. The case of glycerol.

Analytical chemistry·2011
Same journal

The "Twilight Zone" Is a Danger Zone: Why the Occupational-Clinical Divide in Burnout Assessment Is a False Dichotomy.

Evaluation & the health professions·2026
Same journal

Evaluating Equity in AI-Supported Functional Assessment: Agreement Between Clinician Judgment and Digital Metrics in Stroke Rehabilitation.

Evaluation & the health professions·2026
Same journal

Psychometric Properties of the Arabic Version of the PROMIS Sleep Disturbance 8b Short Form Among Nurses.

Evaluation & the health professions·2026
Same journal

Commentary: Systemic Inequities in Japan's Technical Intern Training Program (TITP): Health, Labor, and Legal Vulnerabilities of Foreign Trainees.

Evaluation & the health professions·2026
Same journal

Application of Patient-Reported Outcome Measurements in Traditional Chinese Medicine Clinical Trials for Musculoskeletal Disorders in China: A Registry-Based Analysis.

Evaluation & the health professions·2026
Same journal

Divergent Socioeconomic Pathways to Biologically Uncontrolled Diabetes by Gender: A Bayesian Analysis of NHANES 2021-2023.

Evaluation & the health professions·2026
See all related articles

Evaluating patient outcomes using raw change scores, normative, and ipsative analyses is crucial. The ipsative method proved most effective for analyzing repeated measures data in intermittent claudication patients.

Area of Science:

  • Clinical outcomes analysis
  • Statistical methods in healthcare
  • Patient data monitoring

Background:

  • Longitudinal monitoring of individual patient data is increasingly standard in physician office practices.
  • Evaluating clinical outcomes requires robust analytical methods for repeated measures data.

Purpose of the Study:

  • To compare the effectiveness of raw change score, normative, and ipsative statistical analyses for evaluating clinical outcomes in individual patients.
  • To determine the most suitable method for analyzing functional status changes in patients with intermittent claudication.

Main Methods:

  • The study involved two distinct samples of intermittent claudication patients undergoing vascular surgery office visits.
  • Patients were categorized into interventional management and stable control groups.

Related Experiment Videos

  • Functional status was assessed four times using both generic and disease-specific measures.

    • Main Results:

    • The ipsative statistical analysis method demonstrated the highest consistency with a priori hypotheses.
    • This finding was observed across different types of hypotheses typically evaluated in repeated measures data analysis.
    • The ipsative method offers a reliable approach for longitudinal patient data evaluation.

    Conclusions:

    • The ipsative method is recommended for analyzing repeated measures data in clinical practice, particularly for conditions like intermittent claudication.
    • This statistical approach provides more consistent results aligned with common research hypotheses.
    • Accurate clinical outcome evaluation relies on appropriate statistical methodology.