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Published on: February 19, 2021
Pharmacotherapeutic circles. Results of an 18-month peer-review prescribing-improvement programme for general
L von Ferber1, J Bausch, I Köster
1Primary Healthcare Research Unit, University of Cologne, Germany. Liselotte.vonFerber@medizin.uni-koeln.de
Objective:
To assess the effectiveness of the pharmacotherapeutic circle (PTC), a general practitioner (GP) prescribing-improvement programme to enhance prescribing quality and reduce drug costs.
Design:
Combined pre- and post-intervention time-series design using an internal comparison of subgroups and an external comparative control.
Setting:
Small discussion groups meeting 8 times over 18 months.
Participants:
79 GPs exceeding the mean drug costs/patient of all Hessian physicians by > or = 40%; 10 moderators.
Interventions:
Peer-review feedback of prescription patterns based on guidelines targeting 3 suboptimal prescribing areas: drug prescriptions lacking evidence-based efficacy (target A); presumptive prescribing habits (target B); and underprescribing of new, effective therapies (target C).
Main Outcome Measures And Results:
Significant decreases in prescription rates for target A drugs were recorded for varicose vein medications (p = 0.006), peripheral vasodilators (p = 0.0001) and topical antirheumatics (p = 0.0145), but not for prokinetics/enzymes/digestives. Prescribing of target B drugs such as benzodiazepines and nonsteroidal anti-inflammatory drugs declined markedly (p = 0.0019 and 0.0014, respectively). Target C drug prescriptions such as for opioids and proton pump inhibitors were not significantly increased. Highly significant reductions in prescription costs were observed for target A and B drugs, irrespective of whether GPs were stratified into high, medium or low prescribers. When mean prescribing costs for PTC participants were compared with those of a control group comprising 8000 GPs over a 21-month period, PTC GPs decreased their costs by 2%, whereas drug costs for all Hessian physicians rose by 10%.
Conclusions:
PTCs appear to be an effective method to optimise the quality of drug prescribing and reduce drug costs.
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