The suspected existence of Schistosoma mansoni in Dhanusha district, southern Nepal
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Updated: Oct 18, 2026

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni
Published on: January 14, 2018
J B Sherchand1, H Ohara, S Sherchand
1Tribhuvan University Institute of Medicine, Infectious and Tropical Diseases Research Centre, Kathmandu, Nepal. phrlab@npl.healthnet.org
Abstract:
Eggs resembling those of Schistosoma mansoni have been observed in human stools collected from the inhabitants of Dhanusha district, in southern Nepal. In an attempt to determine if S. mansoni was present, 518 sera collected from subjects from four sites in this district were checked for antibodies to this parasite, in July 1996 and May 1997, using ELISA. Overall, 94 (18.1%) of the subjects were deemed seropositive, with the highest seroprevalence (42.7%) at the one site in Chisipani village and the lowest (1.0%) at one of the three sites in Tulaschichauda village. A follow-up study of Chisipani village, in January 1998, indicated a seroprevalence then of 22.7% (37/110). Although possible intermediate hosts, clinical manifestations and geographical distribution have yet to be explored, the present results indicate that S. mansoni probably does exist in the Dhanusha district of Nepal.
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