[Emergency coronary artery bypass grafting in patients with severe pump failure complicating acute myocardial
1Division of Cardiovascular Surgery, Sakurabashi Watanabe Hospital, Osaka, Japan.
Insights
Emergency coronary bypass grafting improved cardiac function in patients with severe pump failure after myocardial infarction. Both large myocardial infarction and severe ischemia groups showed significant hemodynamic improvements post-surgery.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Cardiac Rehabilitation
Context:
- Severe pump failure complicates acute myocardial infarction (MI).
- Emergency coronary artery bypass grafting (CABG) is a treatment option.
- Understanding the mechanisms of pump failure is crucial for treatment efficacy.
Purpose:
- To evaluate the effectiveness of emergency coronary artery bypass grafting (CABG) in patients with severe pump failure post-myocardial infarction (MI).
- To compare outcomes between patients with large MI alone versus those with severe ischemia.
- To assess changes in cardiac index (CI) and pulmonary wedge pressure (PCWP) post-CABG.
Summary:
- Thirty patients with severe pump failure (Killip's III+) post-MI underwent emergency CABG.
- Patients were divided into Group I (large MI) and Group II (severe ischemia).
- Both groups showed significant improvements in CI and PCWP 72 hours post-surgery, with no significant difference between groups.
Impact:
- Emergency CABG can effectively improve hemodynamic function in severe pump failure post-MI.
- The study suggests CABG is beneficial regardless of the specific mechanism of pump failure (MI vs. ischemia).
- Further research may explore long-term outcomes and refine patient selection for CABG in this population.
Abstract:
Thirty patients with severe pump failure (Killip's degree III or more) complicating acute myocardial infarction (MI) underwent emergency coronary bypass grafting (CABG). Average age was 66 years old and CABG was performed 2.6 days after the onset of MI. The patients were divided into two groups according to the mechanisms that can bring about severe pump failure: 19 patients had large MI alone (G-I). The other 11 patients had severe ischemia occurring either at areas distant from the site of coronary occlusion or in the previous area at risk (G-II). To estimate the ventricular wall motion quantitatively, the left ventricular wall was divided into 17 segments. Each segment was graded on a four-point scale: akinesis, 3; severe hypokinesis, 2; hypokinesis, 1; normal 0. Wall motion score was estimated by summing the number of asynergic segments score. In G-I, Cardiac index (CI (l/min/m2)) increased from 2.03 +/- 0.91 to 2.68 +/- 0.73 and pulmonary wedge pressure (PCWP (mmHg)) decreased from 28 +/- 5 to 15 +/- 5, 72 hours after the surgery (p < 0.01). In G-II, CI increased from 2.17 +/- 0.78 to 3.17 +/- 1.01 and PCWP decreased from 29 +/- 6 to 13 +/- 5 after the surgery (p < 0.01). There was no difference in preoperative and postoperative hemodynamics between two groups. The wall motion score at the risk area did not change postoperatively (from 16 +/- 7 to 17 +/- 9 in G-I, from 15 +/- 8 to 11 +/- 5 in G-II).(ABSTRACT TRUNCATED AT 250 WORDS)
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