Osteoblastic osteogenic sarcoma in a 35-month-old girl. Report of a case

Area of Science:

• Pediatric Oncology
• Orthopedic Oncology
• Skeletal Tumors

Background:

• Osteogenic sarcoma is a primary malignant bone tumor.
• It most commonly affects children and young adults.
• Early diagnosis and treatment are crucial for better outcomes.

Purpose of the Study:

• To report an exceptionally young case of osteoblastic osteogenic sarcoma.
• To contribute to the understanding of rare pediatric bone cancers.
• To emphasize the importance of considering osteosarcoma in young children with bone pain and swelling.

Main Methods:

• Case report of a 2-year, 11-month-old female patient.
• Clinical presentation: pain and swelling of the proximal humerus.
• Diagnosis: osteoblastic osteogenic sarcoma of the humerus.

Main Results:

• The patient presented with symptoms indicative of a bone tumor.
• Histopathological examination confirmed osteoblastic osteogenic sarcoma.
• This patient is the youngest recorded case in a series of 937 osteogenic sarcoma patients at the Mayo Clinic.
• She is one of only six patients younger than 6 years old in the series.

Conclusions:

• Osteoblastic osteogenic sarcoma can occur in very young children.
• This case represents an extremely rare presentation of osteosarcoma.
• Prompt medical evaluation is essential for pediatric bone pain and swelling to ensure timely diagnosis of conditions like osteosarcoma.