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Updated: Jul 28, 2026

Video-rate Scanning Confocal Microscopy and Microendoscopy
Published on: October 20, 2011
Confocal laser scanning microscopy
1Department of Molecular Biology, University of Wisconsin, Madison 53706, USA. paddock@facstaff.wisc.edu
Abstract:
Many technological advancements of the past decade have contributed to improvements in the photon efficiency of the confocal laser scanning microscope (CLSM). The resolution of images from the new generation of CLSMs is approaching that achieved by the microscope itself because of continued development in digital imaging methods, laser technology and the availability of brighter and more photostable fluorescent probes. Such advances have made possible novel experimental approaches for multiple label fluorescence, live cell imaging and multidimensional microscopy.
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