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Large granular lymphocytic leukemia in a mixed breed dog
K W Lau1, S A Kruth, C E Thorn
1Department of Clinical Studies, Ontario Veterinary College, University of Guelph.
The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
|November 26, 1999
Abstract:
A mixed breed dog was diagnosed with large granular lymphocytic leukemia. Immunophenotypic analysis indicated the lymphocytes were CD3+, CD8+ T cells expressing the alpha beta T cell receptor and a leukointegrin, alpha d. Chemotherapy and splenectomy resulted in an initial reduction in the lymphocyte count.