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Long-term chrysotherapy in rheumatoid arthritis
Arthritis and Rheumatism
|February 1, 1979
Summary
Continuing chrysotherapy (gold injections) for rheumatoid arthritis significantly increases remission rates. Prolonged gold therapy is more effective than stopping treatment, even for patients with long-standing disease.
Area of Science:
- Rheumatology
- Pharmacology
Background:
- Chrysotherapy, or gold therapy, is a treatment for rheumatoid arthritis.
- The long-term efficacy of chrysotherapy requires further investigation.
Purpose of the Study:
- To evaluate the long-term efficacy of chrysotherapy in rheumatoid arthritis patients.
- To determine the impact of continued versus discontinued gold injections on remission rates.
Main Methods:
- A 3-year follow-up study of rheumatoid arthritis patients undergoing chrysotherapy.
- Comparison of remission rates between patients who continued gold injections and those who stopped.
Main Results:
- 73% of patients continuing chrysotherapy achieved remission after 3 years.
- Only 6% of patients who stopped gold injections experienced spontaneous remission.
- Both groups initially had comparable, moderately severe rheumatoid arthritis (6-8 years duration).
Conclusions:
- Prolonged chrysotherapy administration enhances treatment efficacy for rheumatoid arthritis.
- Maintenance gold injections should be continued indefinitely in the absence of toxicity.
- Chrysotherapy demonstrates sustained benefits for rheumatoid arthritis management.