Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Verbal semantic memory in temporal lobe epilepsy.

A R Giovagnoli1

  • 1National Neurological Institute C. Besta, Milano, Italy.

Acta Neurologica Scandinavica
|November 30, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A fragment of Steven Schachter's style in behavioral neurology.

Epilepsy & behavior : E&B·2022
Same author

Early and long-term cognitive features in sporadic Creutzfeldt-Jakob disease.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2021
Same author

Cognitive training in Alzheimer's disease: a controlled randomized study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2017
Same author

The course of language functions after temporal lobe epilepsy surgery: a prospective study.

European journal of neurology·2016
Same author

Cognition, behavior, and the role of Epilepsy & behavior in advancing knowledge about epilepsy.

Epilepsy & behavior : E&B·2014
Same author

Can music therapy alleviate psychological, cognitive, and behavioral impairment in epilepsy?

Epilepsy & behavior : E&B·2013

Left temporal lobe epilepsy (TLE) significantly impairs verbal semantic memory, distinct from episodic memory deficits. This semantic memory compromise in TLE may stem from impaired access to semantic-lexical storage.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Temporal lobe epilepsy (TLE) is associated with memory difficulties.
  • These difficulties may extend beyond episodic memory impairment.
  • Specific deficits in semantic memory within TLE require further investigation.

Purpose of the Study:

  • To identify specific semantic memory dysfunctions in TLE patients.
  • To examine the relationship between semantic memory deficits and epilepsy-related variables.
  • To differentiate semantic from episodic memory performance in TLE.

Main Methods:

  • Compared 47 TLE patients and 23 healthy controls using various memory and language assessments.
  • Evaluated expressive/receptive vocabulary, semantic judgment, episodic memory, language abilities, and abstract reasoning.

Related Experiment Videos

  • Utilized Picture Naming, Semantic Questionnaire, Selective Reminding Procedure, Story Recall, Token Test, and Raven's Matrices.

    • Main Results:

    • Left TLE patients showed significant semantic memory impairment compared to controls.
    • Episodic memory was impaired across various epilepsy groups.
    • Naming abilities were more affected than comprehension or semantic judgment in TLE; language and reasoning abilities remained intact.

    Conclusions:

    • Left TLE can lead to substantial verbal semantic memory compromise, potentially due to impaired access to semantic-lexical storage.
    • Differentiating semantic and episodic memory performance aids in understanding memory failures in non-aphasic epilepsy.
    • These memory assessments can complement clinical and neurophysiological methods for localizing epileptic foci.