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Principles and practice of antibiotic therapy
1Department of Restorative/Hospital Dentistry, University of Washington School of Dentistry, Seattle, USA.
Infectious Disease Clinics of North America
|December 1, 1999
Summary
Oral infections present diversely due to complex microbial communities. This review details oral and maxillofacial structures and antibiotic classes for managing these infections.
Area of Science:
- Oral and Maxillofacial Surgery
- Infectious Diseases
- Microbiology
Background:
- The oral cavity hosts a complex microbiome, influencing disease presentation.
- Infections in oral and maxillofacial structures can be acute or chronic, leading to varied clinical manifestations.
- Effective management requires understanding the infection's origin and spread.
Purpose of the Study:
- To review the anatomical domains of oral and maxillofacial structures.
- To provide an overview of antibiotic classes relevant to oral infections.
- To guide surgical and pharmacologic management decisions for oral and maxillofacial infections.
Main Methods:
- Literature review of oral and maxillofacial anatomy.
- Review of major antibiotic classes and their mechanisms of action.
- Analysis of antibiotic usage patterns in relation to infection sites.
Main Results:
- Detailed description of distinct oral and maxillofacial anatomical regions.
- Classification of antibiotics based on spectrum of activity and pharmacokinetics.
- Correlation between infection source, microbial patterns, and appropriate antibiotic selection.
Conclusions:
- Understanding oral anatomy is crucial for diagnosing infection spread.
- Knowledge of antibiotic classes aids in selecting appropriate antimicrobial therapy.
- Tailored treatment strategies improve outcomes for oral and maxillofacial infections.