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Homicidal poisoning with glibenclamide.

R Fernando1

  • 1Faculty of Medicine, University of Colombo, Sri Lanka.

Medicine, Science, and the Law
|December 3, 1999
PubMed
Summary

Homicidal poisoning is rare, but two cases used glibenclamide to induce hypoglycemia. Investigations highlighted the need for toxicology and police work when death causes are unclear.

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Area of Science:

  • Forensic toxicology
  • Clinical toxicology
  • Medicolegal investigations

Background:

  • Suicidal poisoning, particularly with pesticides, is a significant public health issue in Sri Lanka.
  • Homicidal poisoning is comparatively rare in the region.

Observation:

  • This report details two homicide cases involving induced hypoglycemia.
  • The anti-diabetic drug glibenclamide was administered to cause the hypoglycemic state.

Findings:

  • Clinical and medicolegal findings were analyzed in conjunction with court proceedings.
  • The cases underscore the critical role of comprehensive toxicological analysis.
  • Thorough police investigations are essential when the cause of death is ambiguous.

Implications:

  • Highlights the potential for anti-diabetic medications to be used in homicides.
  • Emphasizes the necessity of advanced forensic analysis in medicolegal cases.
  • Stresses the importance of interdisciplinary collaboration between medical examiners and law enforcement.

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