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Updated: Jul 25, 2026

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue
Published on: October 26, 2014
[Epileptic crisis and multiple sclerosis: anatomo-clinical correlation]
M J Murillo1, Y Aladro, B Mompeó
1Servicio de Neurofisiología Clínica, Hospital Ntra. Sra. del Pino, Las Palmas de Gran Canaria, España.
Epilepsy can be an early indicator of multiple sclerosis (MS). This case study suggests a potential causal link between epileptic seizures and the onset of MS, supported by clinical and imaging findings.
Area of Science:
- Neurology
- Clinical Neuroscience
Background:
- Epilepsy is common, while its presentation as an initial symptom of multiple sclerosis (MS) is rare.
- The etiological relationship between epilepsy and MS remains unclear, with coincidental association being a possibility.
Observation:
- A 25-year-old female presented with epileptic seizures as the first manifestation of MS.
- Clinical examination revealed right homonymous inferior quadrantanopsia.
Findings:
- Magnetic resonance imaging (MRI) showed demyelination lesions in the subcortical occipital region and semioval centrum.
- Electroencephalogram (EEG) was pathological, and visual and auditory evoked potential latencies were delayed, alongside a high Tibbling index.
Implications:
- The findings suggest a potential causal association between epilepsy and multiple sclerosis.
- This case highlights the importance of considering MS in young individuals presenting with unexplained seizures and neurological deficits.
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